Sedation and analgesia during bone marrow aspiration in children: Is ketamine and propofol combination (Ketofol) an appropriate agent?

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Ketofol for bone marrow aspiration and lumbar puncture in Children with ALL

Abstract Background Ketofol is usually using as a sedative drug during painful procedures now. That Provides sedation, analgesia and rapid recovery. The aim of this study was to compare the efficacy, respiratory and hemodynamic profiles, and side effects of two various combination of ketamine and propofol in patients undergoing bone marrow aspiration (BMA) and lumbar puncture (LP). Materials...

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Ketofol: A Combination of Ketamine and Propofol

Sedative and analgesic agents are frequently used for procedural sedation. Titration of anesthetic doses should be done cautiously and the patients should be continuously monitored. So far, an ideal intravenous anesthetic agent is none [1,2]. A combination of ketamine and propofol has several ideal anesthetic properties. Several clinical studies of the use of ketofol have been evaluated. To dat...

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Ketamine-propofol combination (ketofol) versus propofol alone for emergency department procedural sedation and analgesia: a randomized double-blind trial.

STUDY OBJECTIVE We determine whether a 1:1 mixture of ketamine and propofol (ketofol) for emergency department (ED) procedural sedation results in a 13% or more absolute reduction in adverse respiratory events compared with propofol alone. METHODS Participants were randomized to receive either ketofol or propofol in a double-blind fashion. Inclusion criteria were aged 14 years or older and Am...

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مقایسه دو ترکیب دارویی پروپوفول-آلفنتانیل و میدازولام-کتامین برای ایجاد آرام‌بخشی و بی‌دردی در ضمن آسپیراسیون مغز استخوان در کودکان

Background: Invasive procedures such as bone marrow aspiration in children with oncologic malignancies are painful and may produce anxiety for both patients and their parents. Various pharmacologic treatments have been used to sedate children undergoing bone marrow aspiration. This prospective randomized study was designed to compare the effectiveness of these combinations, as well as their ass...

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Is ketamine–propofol mixture (ketofol) an appropriate alternative induction agent for electroconvulsive therapy?

therefore their side-effects on these systems could be reduced by administering a combination of them at a lower dose.[9] In recent studies done on patients undergoing ECT, it showed that using sub-anesthetic ketamine and low-dose propofol could increase the seizure duration, provide hemodynamic stability and earlier recovery compared with the use of a full dose of propofol alone. In a study by...

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ژورنال

عنوان ژورنال: Indian Journal of Medical and Paediatric Oncology

سال: 2013

ISSN: 0971-5851

DOI: 10.4103/0971-5851.125268